Ushma Issar is the Founder and CEO of Rypple, a “health-ing” hub based in the Netherlands that works to shift health systems from reactive treatment to proactive well-being. She leads strategy, partnerships, and innovation to drive systemic change in global health. At Rypple, she oversees the Predictive ROI Engine for Prevention—a platform that models and prioritizes preventive health investments using advanced analytics, economics, and policy simulations. Ushma also drives the Business Innovation Base, partnering with startups and corporates to scale prevention-oriented solutions. With over a decade of experience in the global medical device industry, Ushma brings a cross-sector perspective to health transformation. She is passionate about using fiscal and policy levers to make “health-ing” economically and politically viable.